Snakebite survival may depend on solving venom mysteries
By kingsnake.com · July 3, 2014 6:02 am
Not all venomous snakebites are created equal -- and neither are all antivenoms. Now researchers at the Liverpool School of Tropical Medicine (LSTM) have identfied important differences in venoms that may lead to breakthroughs in snakebite treatment worldwide.
From Phys.org:
LSTM's Dr Nicholas Casewell, first author and NERC Research Fellow, said: "Our work shows that venom variation observed between related snake species is the result of a complex interaction between a variety of genetic and postgenomic factors acting on toxin genes. This can involve different genes housed in the genome being turned on or off in different snakes at different stages of venom toxin production. Ultimately, the resulting venom variation results in significant differences in venom-induced pathology and lethality and can undermine the efficacy of antivenom therapies used to treat human snakebite victims."Read more... Photo: kingsnake.com user HerpLver
